It was a pleasure to work with the team led by Francois St-Pierre on this collaborative project. We describe new genetically encoded voltage indicators, JEDI3sub and JEDI3hyp, with enhanced performance for detecting subthreshold voltage responses in neurons. These new sensors can be used with various microscopy methods, including resonant scanner 2P imaging. Mate and Shanii in the lab used JEDI3hyp to image subthreshold depolarization and hyperpolarization in PV interneurons

We celebrated Christmas with a fine dinner the 3rd time this year - thank you to all lab members for your hard work! Stay tuned for exciting new papers in the new year.

Allison Tirado is a first year student in our Master of Science in Biomedical Sciences program. She graduated from Trinity University with a BSc in Neuroscience, and she is interested in investigating GABAergic interneurons and learning more about epilepsy.